{"id":4175,"date":"2026-06-23T05:34:15","date_gmt":"2026-06-23T05:34:15","guid":{"rendered":"https:\/\/tampamovingjournal.com\/?p=4175"},"modified":"2026-06-23T05:34:15","modified_gmt":"2026-06-23T05:34:15","slug":"new-lsd-based-drug-eases-depression-symptoms-in-late-stage-trial","status":"publish","type":"post","link":"https:\/\/tampamovingjournal.com\/?p=4175","title":{"rendered":"New LSD-based drug eases depression symptoms in late-stage trial"},"content":{"rendered":"<div><div><div>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" class=\"wp-image-4174\" height=\"432\" src=\"https:\/\/tampamovingjournal.com\/wp-content\/uploads\/2026\/06\/1814c47823284c1a6158f0f362bdc990.webp\" width=\"764\" srcset=\"https:\/\/tampamovingjournal.com\/wp-content\/uploads\/2026\/06\/1814c47823284c1a6158f0f362bdc990.webp 764w, https:\/\/tampamovingjournal.com\/wp-content\/uploads\/2026\/06\/1814c47823284c1a6158f0f362bdc990-300x170.webp 300w\" sizes=\"auto, (max-width: 764px) 100vw, 764px\" \/><\/figure>\n <span>article<\/span><\/div> <div><div><p><span>FILE-A lab technician prepares a solution that will be used in a clinical trial. (Photo by Chip Somodevilla\/Getty Images)<\/span> <!-- --><\/p><p>Read more <a href=\"https:\/\/tampamovingjournal.com\/?p=4172\">Plant-based meats recalled over possible plastic in the nuggets and patties<\/a><\/p> <div>Expand<\/div><\/div><\/div> <!-- --><\/div> <!-- --> <!-- --><p>A new LSD-based experimental pill can substantially reduce symptoms of major depression in patients in a late-stage trial.\u00a0<\/p> <p>Definium Therapeutics, biopharmaceutical company, told Reuters that the experimental drug helped patients record significantly lower scores on a standard depression scale, meeting the clinical \u200btrial&#8217;s main objective.<\/p> <!-- --><h2>What is the new LSD-based drug?<\/h2> <!-- --><div><\/div> <!-- --><p>Dig deeper:<\/p> <!-- --><p>DT120 is a pill that is part of a \u2060class of drugs known as classic psychedelics, which temporarily alter perception, mood \u200band thinking. Reuters reported that it\u2019s a pharmaceutical formulation of LSD also known as lysergide \u200band works by activating serotonin receptors in the brain.\u00a0<\/p><p>Read more <a href=\"https:\/\/tampamovingjournal.com\/?p=4169\">Sloth imports to Florida now require a new wildlife permit: FWC memo<\/a><\/p> <!-- --><p><strong>RELATED:<\/strong><strong><u> FDA approves first-of-its-kind nasal spray to treat depression<\/u><\/strong><\/p> <!-- --><p>To determine the effectiveness of the drug, Definium Therapeutics conducted a clinical trial using the drug with 149 participants between the age of 18 and 74 years old with major depressive disorder (MDD), which is the second-most common mental health disorder in the United States, with over 21 million Americans experiencing a significant depressive incident annually.\u00a0<\/p> <!-- --><p>Definium said the data brings it closer to an FDA submission, and it was running a second \u200blate-stage depression trial.<\/p> <!-- --><p>According to Reuters, the drug was generally tolerated with the majority of adverse \u2060events mild to moderate, happening primarily on the day of dosing, and no severe safety issues or increases in suicidal thoughts observed by researchers.<\/p><p>Read more <a href=\"https:\/\/tampamovingjournal.com\/?p=4167\">Calvin Coolidge\u2019s historic visit still felt at Bok Tower Gardens<\/a><\/p> <!-- --> <!-- --><p><br\/>\u00a0<\/p> <!-- --> <!-- --> <\/div>","protected":false},"excerpt":{"rendered":"<p>The latest LSD-based drug was used in a clinical trial to support patients with major depression in an initial step in bringing the drug closer to Food and Drug Administration submission and review.<\/p>\n","protected":false},"author":1,"featured_media":4173,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[49,59],"tags":[51,60],"class_list":["post-4175","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","category-mental-health","tag-health","tag-mental-health"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - 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